BIOSCIENCE

Proteins have
more to say.

Much of it is written in the sugars attached to them.
We’re building the technology to read it, protein by protein.

The protein sequence stays the same.
The sugar patterns on it can change.

Sugars, added after the sequence by enzymes, with no gene as template.

First genes. Then proteins.
Now the sugars on them.

The genome gave us the instructions: which proteins a cell can make. It was the first era of reading biology at scale, and it changed medicine.

Today's tests count proteins.
They don't read them.

Two samples can contain similar amounts of the same protein and still differ in the sugars attached to it. Today's tests miss that difference: most count the protein and ignore its sugars, and the few that detect a sugar can't tell which protein carries it.

Until now, reading the sugar on the protein took mass spectrometry in a specialist lab.

one conditionanother condition
Two illustrative groups overlap in protein amount but differ in the share carrying a particular glycoform.

Conceptual illustration

A platform that reads the sugar patterns on proteins,
built to become routine clinical tests.

Pick a protein. Our platform measures how much of it is there, and what share of it carries a particular sugar pattern: the numbers a clinician can act on. Glycosylation is where we start; the same approach extends to other modifications.

Get in touch

For partnerships, collaborations or questions about Trilis, leave us a note and a way to reach you.